MyBioSource.com's TRIM32 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The TRIM32 Antibody was generated using TRIM32 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Function: Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin) and promotes its degradation. May ubiquitinate BBS2. May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo. Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo.
Subunit Structure: Interacts with DTNBP1. It self-associates.
Post-translational Modifications: Ubiquitinated.
Similarity: Belongs to the TRIM/RBCC family